Before You Book a Session Day

A two-minute check. Two things worth knowing before you pick a date: what rules a session out, and what you're agreeing to do beforehand. Most people are fine on both — but a couple of the holds need weeks of lead time, and nobody likes finding that out after a deposit.

Any medication change happens through your prescriber — never on your own. Some of these are dangerous to stop abruptly. We are not your prescriber, and we will never ask you to stop a medication to qualify for a session.

Don't book if any of these apply

You're under 21
Schizophrenia, schizoaffective disorder, or another psychotic disorder
Bipolar I, or any manic or psychotic episode you've ever had — including one triggered by a substance or medication
You're in psychosis or mania right now
You take lithium
You take an MAOI — Nardil, Parnate, Marplan, Emsam, Azilect, or a botanical one (Syrian rue, ayahuasca)
You're pregnant or breastfeeding
You're actively suicidal with a plan, or had a recent attempt
Unstable heart disease — recent heart attack or stroke, unstable angina, significant arrhythmia, uncontrolled high blood pressure
An uncontrolled seizure disorder

A parent or sibling with schizophrenia or bipolar I isn't an automatic no — but it's a real conversation, so mention it early.

You'll need to be able to hold these

If any line here is a no for you, say so before you book rather than after.

GLP-1 medicationsOzempic, Wegovy, Rybelsus, Mounjaro, Zepbound, Trulicity, Victoza, Saxenda — including compounded versions. They slow digestion, which turns a normal wave of nausea into vomiting on a fasted session day.

4 weeks before

Benzodiazepines you take as neededXanax, Ativan, Klonopin, Valium, Restoril, Librium — plus Ambien, Lunesta, Sonata. They blunt the experience, sometimes enough to waste the day.

48 hours before

Alcohol and cannabisAny form — edibles and vapes included

48 hours before

Serotonergic supplementsSt. John's Wort, 5-HTP, L-tryptophan, SAM-e, kratom — and cough medicine with DXM (Robitussin DM, Delsym, NyQuil)

2 weeks before

StimulantsAdderall, Vyvanse, Concerta, Ritalin, Focalin, Dexedrine, Provigil

Day of

MirtazapineRemeron

Taper, weeks ahead

AntipsychoticsSeroquel, Risperdal, Abilify, Zyprexa, Latuda

Tell us early

TramadolUltram, Ultracet

Tell us early

Benzodiazepines you take every dayNot a hold — stopping abruptly is dangerous, so this needs a plan with your prescriber

Months ahead

Your SSRI or SNRI is not on this list. We don't require you to taper an antidepressant — here's why.

You may need a note from your doctor

If you have a heart condition, high blood pressure, a seizure history, a prior stroke, diabetes, or significant liver or kidney disease, we need a short note from your treating clinician saying they have no objection. It doesn't need to endorse psilocybin — only to say your body can handle several hours of elevated heart rate with limited food. These take a few weeks to get, so start early.

What the day itself takes

Up to seven hours on site — clear the whole day
A light breakfast, then nothing before the medicine
You can't drive afterward, so a named person takes you home
A preparation session first, and integration on the calendar before you come in

Not sure where you land? Ask before you book — it takes one short conversation, and "not right now" is a perfectly good answer.

Ask a Question

General information about what our program requires, not medical advice, and not a complete list. Whether natural medicine is appropriate for you is decided through screening with a licensed facilitator. The fuller picture is on our contraindications and safety and screening pages. Legal in Colorado under Prop 122 for adults 21+.