The Psilocybin Journey Series
Some of the deepest work isn't a single experience — it's a structured course. Two guided journeys, a measured step up in dose, and integration between: the shape behind the most durable research in psilocybin-assisted therapy.
Why a series, not a single session
A single psilocybin journey can be genuinely transformative. But for depression and other deep-rooted patterns, the research is clearest when the work is structured as a course rather than a one-off. In one large trial, a single dose produced a strong antidepressant effect at three weeks that had faded by twelve. In the trial with the most durable results, participants did two sessions — the second at a higher dose — and response and remission were still holding a full year later.
The Journey Series is built around that model: a first journey to open the work, an integration interval to let it settle, and a second journey that steps up in dose based on how you responded. It's a clinician-led, evidence-informed way to give the process the room it often needs — with a third journey available if the work calls for it.
The Research Behind a Multi-Session Approach
Peer-reviewed trials point to a structured, multi-session model as the one with the most durable results for depression. The findings are promising and still emerging; outcomes vary by individual.
response and remission from depression sustained at 12 months in a two-session, escalating-dose protocol
Gukasyan et al., J. Psychopharmacology, 2022 (Johns Hopkins)the dosing structure behind the most durable trial data — a first journey followed by a higher-dose second
Davis et al., JAMA Psychiatry, 2021 (Johns Hopkins)single-dose antidepressant effects were not sustained at 12 weeks in a large trial — part of the rationale for a structured series
Goodwin et al., NEJM, 2022 (COMPASS)How the Series Works
Two structured journeys with an integration interval between — each journey a complete cycle of preparation, administration, and integration.
Preparation & First Journey
Screening and a preparation session to build trust and set intentions, then your first administration session with your facilitator present throughout — followed by two integration sessions to begin making meaning of what surfaced.
Second Journey
Two to four weeks later, a second administration session at a measured step up in dose, informed by how you responded the first time. The interval lets the first experience settle and shapes intentions for going deeper — the cadence used in the clinical trials.
Deeper Integration
Two further integration sessions after the second journey — the stretch where insight becomes durable change. Integration is where the most lasting gains consolidate, and the series is built to give it real room.
An optional third journey
For some, two journeys complete the work. For others, a third — booked as a continuation once the second has been integrated — extends the arc. It's always a shared decision between you and your facilitator, never automatic. The series is a structure that serves the work, not a fixed number you're obligated to finish.
The Shape of the Series
Seven guided touchpoints across two journeys — one preparation, two administration sessions at an escalating dose, and four integration sessions, where the experience becomes lasting change.
Four integration sessions — two after each journey — because lasting change is built between and after the journeys, not only during them.
Pricing
The series bundles two complete journeys, with a returning-participant rate for continuing later.
Two separate journeys also run $5,000 — but include just two integration sessions. The series is the same price with two more integration sessions (a $350 value) and the escalating-dose cadence built in.
Insurance: Natural medicine services are not currently covered by insurance. Payment is arranged before each administration session.
Superbill: Available for preparation and integration sessions for potential out-of-network reimbursement, depending on your plan.
HSA/FSA: These funds may be used toward natural medicine services. Consult your plan administrator.
Deposit & cancellation: A $500 deposit reserves each session day and applies toward your fee. See our deposit & cancellation policy for details.
Who the Series Is For
A structured course suits some goals better than a single session. Eligibility is always confirmed through screening.
Depression that hasn't fully lifted
Especially where a single experience helped but the effect faded, or where standard treatments haven't gone far enough. The most durable trial data comes from a two-session model.
Deep, sustained work
When your goals call for more than one experience — building on a first journey rather than hoping it does everything at once.
People who've journeyed before
If you've completed a first journey and want to continue, the series (or a returning-participant journey) is the natural next step.
Important: Psilocybin services are not appropriate for everyone, and a series is not right for every candidate. A thorough screening precedes any session — psilocybin is generally not recommended with a personal or family history of psychosis or certain other conditions, and some medications require review. No outcome can be guaranteed.
Frequently Asked Questions
Common questions about the multi-session journey series.
Why more than one journey?
How far apart are the journeys?
Why does the second dose go up?
Is escalating the dose allowed under Colorado law?
Do I have to commit to the whole series upfront?
What if two journeys turn out to be enough?
How much does the series cost?
Is this different from bringing a partner to journey with me?
Tanner Oliver, LCSW
Licensed Clinical Social Worker · State-Licensed Natural Medicine Facilitator
Tanner leads natural medicine services at Front Range Treatment Center. As a licensed clinical social worker and a state-licensed natural medicine facilitator under Colorado's Natural Medicine Health Act, he designs and guides each journey series — preparation, the administration sessions, and the integration work between and after.
His clinical focus with adults spans depression, anxiety, emotional dysregulation, and trauma — the same evidence-based lens he brings to the multi-session model.
Is a Journey Series Right for You?
Start with a free 15-minute consultation. We'll talk through your goals and whether a single journey or a structured series is the better fit — no commitment required.
Calls available Mon–Thurs · We respond within 1 business day